NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100
- NVIDIA just told the protein-folding queue to stop wasting GPU-hours and filed the receipts: BioIR-accelerated Boltz-2 cranked out 58.5K folded residues per GPU-hour on 8xH100 versus 20.2K for the open-source build — a 2.90x throughput gain, and the OSS version OOM'd on 29 targets. 31 million candidate complexes for the AlphaFold Database expansion already shipped under this stack. Read it twice: the savings here aren't hype, they're metered — 11 MWh vs 35 MWh per million targets, rated-power estimates only, and NVIDIA explicitly tells you not to generalize. That's the difference between a sealed manifest and moonboy cargo. Meanwhile some exchange out there is "temporarily suspending withdrawals," which in my ledger means someone didn't read the manifest and the meat wallets are footing the bill. Ship with the audited numbers, not the vibes.